Prof Stephen Marks

Professor of Paediatric Nephrology and Transplantation
Professor Stephen Marks 
Professor Stephen Marks 

Overview

Professor Stephen Marks, MD MSc MRCP DCH FRCPCH is a Consultant Paediatric Nephrologist and Clinical Lead for renal transplantation at Great Ormond Street Hospital (GOSH) since 2004. He leads the largest kidney transplantation unit in the United Kingdom for children and young people. He is Professor of Paediatric Nephrology and Transplantation at University College London Great Ormond Street Institute of Child Health and Director of the NIHR GOSH Clinical Research Facility.

He is passionate about providing the highest quality clinical care to all children with kidney diseases. He was previously named in The Times Top 100 Children’s Doctors in the United Kingdom.

He is active in research and is the theme lead for high intensity early phase clinical trials as well as PPIEP for NIHR GOSH Biomedical Research Centre and chair of the British Association for Paediatric Nephrology and UK Renal Registry Audit and Informatics committee having previously been the chair of the National Health Service Blood and Transplant Paediatric Kidney Advisory Group.

His research continues to date in the fields of renal transplantation (including innovative drug trials concerning new anti-rejection therapies and assessment of children post-renal transplantation), systemic lupus erythematosus and vasculitis. He is on the editorial board for “British Journal of Renal Medicine” and is associate editor for “Transplantation”,“Pediatric Nephrology” and “Pediatric Transplantation”, which are the journals of The Transplantation Society, the International Pediatric Nephrology Association and the International Pediatric Transplant Association (IPTA) respectively. Having been chair of the Publications and Communications Committee, he is now a Councillor of IPTA.

Credentials

  • Renal transplantation 
  • Systemic lupus erythematosus
  • Vasculitis
  • Glomerular diseases 
  • Urinary tract infections
  • Hypertension

Training:

  • MBChB from University of Glasgow
  • MRCP (UK)
  • DCH (London)
  • MSc in Clinical Paediatrics from University College London
  • FRCPCH
  • MD (University of London)
  • Paediatric training in the hospitals of Glasgow, Newcastle upon Tyne, London and Brisbane
  • Paediatric nephrology training in London and Toronto

Membership:

  • UK Kidney Association 
  • British Transplantation Society 
  • Royal College of Paediatrics and Child Health
  • British Association for Paediatric Nephrology 
  • European Society for Paediatric Nephrology 
  • European Society of Organ Transplantation
  • International Pediatric Nephrology Association 
  • International Pediatric Transplant Association 
  • International Pediatric Hypertension Association 
  • International Society of Nephrology 
  • General Medical Council 
  • British Medical Association 
  • Medical Defence Union 

 

  • Renal transplantation (including innovative drug trials concerning new anti-rejection therapies and assessment of children post-renal transplantation) 
  • Systemic lupus erythematosus and vasculitis (including studies of the aetiopathogenesis, management and outcome of childhood onset SLE and lupus nephritis) 
  • Hypertension (including genetic linkage and familial studies of renovascular hypertension and clinical studies on the management and long-term prognosis of children with renovascular hypertension) 

News & Publications

Mudalige NL, Brown C, Marks SD.  “The impact of donor and recipient sex on kidney allograft survival in pediatric transplant recipients.”  Pediatr Nephrol 2022; 37(1): 209 -216.

Rangoonwala S, Marks SD.  “Kidney transplantation outcomes for children and young people with lupus nephritis.”  Pediatr Transplant 2022; 26(1): e14193.

Preka E, Sekar T, Lopez Garcia SC, Shaw O, Kessaris N, Mamode N, Stojanovic J, Sebire NJ, Kim JJ, Marks SD.  “Outcomes of paediatric kidney transplant recipients using the updated 2013/2017 Banff histopathological classification for antibody-mediated rejection.”  Pediatr Nephrol 2021; 36(8): 2575 - 2585.

Sinha R, Agrawal N, Xue Y, Chanchlani R, Pradhan S, Raina R, Marks SD. “Use of rituximab in paediatric nephrology.”  Arch Dis Child 2021; 106(11): 1058 - 1065.

Marlais M, Martin K, Marks SD.  “Improved renal allograft survival for pre-emptive paediatric renal transplant recipients in the United Kingdom.”  Arch Dis Child 2021; 106(21): 1191 - 1194.

Kim JS, Marlais M, Balasubramanian R, Muorah M, Inward C, Smith GC, Reynolds BC, Yadav P, Morgan H, Shenoy M, Tse Y, Hussain F, Grylls S, Kessaris N, Sinha MD, British Association for Paediatric Nephrology, Marks SD.  “UK national study of barriers to renal transplantation in children.”  Arch Dis Child 2021; 106(4): 384 - 386.

Plumb L, Casula A, Pyart R, Evans KM, Inward C, Medcalf J, Marks SD.  “The 21st UK Renal Registry Annual Report: a summary of analyses of paediatric data in 2017.” Nephron 2020; 144(2): 67 - 71.

Preka E, Ellershaw D, Chandler N, Ahlfors H, Spencer H, Chitty L, Fenton MJ, Marks SD.  "Cell free DNA in paediatric solid organ transplantation using a new detection method of separating donor-derived from recipient cell free DNA." Clin Chem 2020; 66(10): 1300 - 1309.

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