Our research

This section highlights just a few examples from 800 active research projects being carried out by Great Ormond Street Hospital and the UCL Institute of Child Health (ICH).


A collaborative partnership

We are the UK's leading paediatric research institution. We put research at the heart of what we do because we want to find new and better ways to help the children we care for.

With our dedicated research partner, the UCL Institute of Child Health (ICH), we are Europe's largest academic centre for research and education in children's health and disease.

The hospital and ICH are also part of UCLPartners, one of five academic health science systems in the UK.

This collaborative approach is central to our thinking and, in 2010, we strengthened relationships with more than 60 NHS Trusts and over 90 UK universities, as well as other research institutes and international research partners. 

Five-year research strategy

Building these relationships is an important part of our five-year research strategy, launched in 2010. To fully realise the strategy, we have also been investing in new technology, improving our infrastructure and investing in excellent researchers and their work.

An area of medical research that is especially relevant to Great Ormond Street Hospital is the application of treatments designed for adults to children. Although a treatment may be completely safe for a mature patient, dose levels and side effects need to be carefully investigated when treating developing children.

This is particularly important in paediatric oncology. Chemotherapy and radiotherapy can have severe side effects; too little intervention can run the risk of the cancer recurring.

Research highlights

  • More than 2,250 patients from Great Ormond Street Hospital were included in studies adopted into the National Clinical Research Network Portfolio.

  • Forty research studies were conducted in the Somers Clinical Research Facility, with more than 220 patients attending 932 research appointments.

  • 233 clinical trials of new therapies were set up in 2010.

  • By the end of 2010, we had 13 active research projects funded by the National Institute of Health Research and 16 active research projects funded by the EU.

  • 551 young patients were recruited to take part in research studies at GOSH through the Medicines for Children Research Network.

  • Our research output includes more than 1,000 peer-reviewed publications each year as well as contributions to national reports and committees that guide national child health policies.

Read more about some of the amazing breakthroughs in paediatric medicine led by Great Ormond Street Hospital.