Immunology

Great Ormond Street Hospital offers a comprehensive diagnostic and treatment service for all primary and immunodeficiency disorders.

The Immunology department offers specialist services for investigation and management of infants and children up to the age of 16 who may be affected by primary immunodeficiencies of all degrees of severity.

The immunology team includes consultants, specialist nurses, junior doctors, psychologists, ward nurses and play specialists. Most outpatient care is supervised by a lead consultant working in collaboration with specialist nurses, while the other members of the team are involved in any day-case or inpatient stays.

Other specialists closely involved with the department include social workers, dietitians and physiotherapists.

Conditions we treat

The Immunology department treats a number of immunodeficiency disorders. The main primary immunodeficiency disorders include:

  • severe combined immunodeficiency
  • X-linked agammaglobulinemia
  • common variable immunodeficiency
  • hyper-IgM syndromes
  • Wiskott-Aldrich syndrome
  • X-linked lymphoproliferative syndrome
  • transient hypogammaglobulinemia of infancy
  • chronic granulomatous disease
  • chromosome 22q11 microdeletion syndrome
  • ataxia telangiectasia
  • C1 esterase inhibitor deficiency

Meet the team

Dr Cathy Cale
Consultant Paediatric Immunologist/Immunopathologist/Honorary Senior Lecturer
Special interest(s): Chediak-Higashi syndrome.

Dr Graham Davies  
Consultant Paediatric Immunologist/Honorary Senior Lecturer
Special interests: Hyper-IgM syndrome, C1 esterase inhibitor deficiency and ataxia telangiectasia.

Professor Bobby Gaspar 
Reader/Honorary Consultant in Paediatric Immunology
Special interests: X-linked lymphoproliferative syndrome and other EBV-related PIDs, bone marrow transplantation and gene therapy for PID.

Professor David Goldblatt 
Professor of Vaccinology and Immunology/Honorary Consultant in Paediatric Immunology
Special interest: chronic granulomatous disease.
 
Dr Alison Jones  
Consultant Paediatric Immunologist/Honorary Senior Lecturer
Special interests: X-linked agammaglobulinemia, common variable immunodeficiency and chromosome 22q11 microdeletion syndrome.

Professor Adrian Thrasher
Professor in Paediatric Immunology/Honorary Consultant Immunologist
Special interest(s): Wiskott Aldrich syndrome; gene therapy for PID.

Dr Waseem Qasim
Senior Lecturer in Paediatric Immunology/Honorary Consultant Immunologist
Special interest(s): BMT; cellular therapies.