Prof Paul Brogan

Professor of Vasculitis and Consultant Paediatric Rheumatologist

Overview

Paul Brogan is Professor of Vasculitis and Honorary Consultant Paediatric Rheumatologist in the Rheumatology department. He specialises in rare inflammatory diseases of the young including Vasculitis, autoinflammatory diseases and autoimmune diseases including Arthritis of the young.

Credentials

  • Vasculitis
  • Periodic fevers and other autoinflammatory diseases
  • Autoimmune diseases
  • Arthritis of the young (JIA)
  • Genetics of inflammatory disease of the young
  • Clinical trials
  • Other translatable research

Training:

  • BSc (First class Hons)
  • MBChB (Hons)
  • MSc
  • PhD: studying the pathogenesis of systemic Vasculitis in children 
  • MRCPCH/FRCPCH 

Membership: 

  • British Medical Association (BMA)
  • British Society for Paediatric and Adolescent Rheumatology
  • Paediatric Rheumatology European Society
  • Paediatric Rheumatology International Trials Organisation
  • Royal Society of Medicine
  • European Vasculitis Study Group
  • International Society of Systemic Autoinflammatory Diseases
  • Secretary of the Vasculitis Working Party for the Paediatric Rheumatology European Society
  • Member of the scientific committee of the MCRN/ARUK paediatric rheumatology clinical studies group
  • UK Paediatric advisor to the Behçet’s Syndrome Society, UK
  • Scientific adviser for Societi (Kawasaki disease, UK)
  • First fully dedicated senior clinical academic working in the field of paediatric Vasculitis in the UK and Europe
  • Rare inflammatory diseases of the young including Vasculitis, acute inflammatory disease, autoimmune disease and Arthritis. 

Insurers

Prof Paul Brogan is covered by the following insurers:

News & Publications

Professor Paul Brogan has been involved in over 120 peer-reviewed scientific publications as well as four text books and more than 10 international book chapters.

Some of his more recent peer reviewed articles include:

Omoyinmi, E., Standing, A., Keylock, A., Price-Kuehne, F., Melo-Gomes, S., Rowczenio, D., Nanthapisal, S., Cullup, T., Nyanhete, R., Ashton, E., Murphy, C., Clarke, M., Ahlfors, H., Jenkins, L., Gilmour, K., Eleftheriou, D., Lachmann, HJ., Hawkins, P.N., Klein, N., Brogan, P.A., 2017. Clinical impact of a targeted next-generation sequencing gene panel for autoinflammation and vasculitis. PLoS One

Groot, N., Graeff, N., Avcin, T., Bader-Meunier, B., Brogan, P.A., Dolezalova, P., Feldman, B., Kone-Paut, I., Lahdenne, P., Marks S.D., McCann, L., Ozen, S., Pilkington, C., Ravelli, A., Royen-Kerkhof, A.V., Uziel, Y., Vastert, B., Wulffraat, N., Kamphuis, S., Beresford, M.W., 2017. European evidence-based recommendations for diagnosis and treatment of childhood-onset systemic lupus erythematosus: the SHARE initiative. 

Groot, N., Graeff, N., Avcin, T., Bader-Meunier, B., Dolezalova, P., Feldman, B., Kenet, G., Koné-Paut, I., Lahdenne, P., Marks, SD., McCann, L., Pilkington, CA., Ravelli, A., van, Royen-Kerkhof, A., Uziel, Y., Vastert, SJ., Wulffraat, N.M., Ozen, S., Brogan, P., Kamphuis, S., Beresford, M.W., 2017.  European evidence-based recommendations for diagnosis and treatment of paediatric antiphospholipid syndrome: the SHARE initiative. Ann Rheum Dis.

Nanthapisal, S., Omoyinmi, E., Murphy, C., Standing, A., Eisenhut, M., Eleftheriou, D., Brogan, P., 2017. Early-Onset Juvenile SLE Associated with a Novel Mutation in Protein.

Standing, A.S., Malinova, D., Hong, Y., Record, J., Moulding, D., Blundell, M.P., Nowak, K., Jones, H., Omoyinmi, E., Gilmour, K.C., Medlar, A., Stanescu, H., Kleta, R., Anderson, G., Nanthapisal, S., Gomes, S.M., Klein, N., Eleftheriou, D., Thrasher, A.J., Brogan, P.A., 2017. Autoinflammatory periodic fever, immunodeficiency, and thrombocytopenia (PFIT).

Nanthapisal, S., Murphy, C., Omoyinmi, E., Hong, Y., Standing, A., Berg, S., Ekelund, M., Jolles, S., Harper, L., Youngstein, T., Gilmour, K., Klein, N.J., Eleftheriou, D., Brogan, P.A., 2017. Deficiency of Adenosine Deaminase Type 2: A Description of Phenotype and Genotype in Fifteen Cases. Arthritis Rheumatol. 68(9). Pp. 2314-22. 

Nanthapisal, S., Klein, N. J., Ambrose, N., Eleftheriou, D., Brogan, P.A., 2016. Paediatric Behçet's disease: a UK tertiary centre experience. Clin Rheumatol. 

Brehm, A., Liu, Y., Sheikh, A., Marrero, B., Omoyinmi,  E., Zhou, Q., Montealegre, G., Biancotto, A., Reinhardt, A., Almeida, de Jesus, A., Pelletier, M., Tsai, WL., Remmers, E.F., Kardava, L., Hill, S., Kim, H., Lachmann, H.J., Megarbane, A., Chae, JJ., Brady, J., Castillo, R.D., Brown, D., Casano, A.V., Gao, L, Chapelle, D., Huang, Y., Stone, D., Chen, Y., Sotzny, F., Lee C.C, Kastner, D.L., Torrelo, A., Zlotogorski, A., Moir, S., Gadina, M., McCoy, P., Wesley, R., Rother, K.I., Hildebrand, P.W., Brogan, P., Krüger, E., Aksentijevich, I., Goldbach-Mansky., 2015. Additive loss-of-function proteasome subunit mutations in CANDLE/PRAAS. J Clin Invest. 125(11). Pp. 4196-211. 

Shah, V., Christof, G., Mukasa, T., Brogan, K.S., Wade, A., Eleftheriou, D., Levin, M., Tulloh, R.M., Almeida, B., Dillon, M.J., Marek, J., Klein, N., Brogan, P.A., 2015. Cardiovascular status after Kawasaki disease in the UK. Heart. 10(20) pp. 1646-55. 

Eleftheriou, D., Varnier, G., Dolezalova, P., McMahon, A.M., Al-Obaidi, M., Brogan, P.A., 2015. Takayasu arteritis in childhood: retrospective experience from a tertiary referral centre in the United Kingdom. Arthritis Res Ther. 17(1) pp. 36. 

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